Scientific Evidence for Our Hawaiian Tinctures

Our Hawaiian tinctures—from noble kava and blue turmeric to native mamaki—are backed by peer-reviewed research highlighting their composition, safety, and traditional uses. These studies underscore the quality, consistency, and cultural significance of our regeneratively grown plants, empowering your personal wellness journey or retail lineup with trusted, science-supported choices. Explore the evidence below.

🌿 Noble Kava: Composition & Safety

Key Takeaways

  • High Kavalactone Content: Noble kava contains 6–15% total kavalactones, with up to 30% kavain, supporting relaxation.
  • Proven Safety: Low flavokavains (e.g., FKB <0.3 mg/g) reduce hepatotoxicity risks.
  • Superior Efficacy: Balanced chemotype (e.g., 423561) for optimal effects at 60–280 mg/day.
  • Quality Assurance: HPLC-verified purity from noble roots.

Supporting Studies

Kava as a Clinical Nutrient

Wu, A. G., et al. (2020). Nutrients.

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Comparison of Kava Varieties

Lebot, V., et al. (2016). Journal of Food Composition and Analysis.

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Kavalactone Content in Hawaiian Kava

Tawake, R. S., et al. (2015). Journal of Food Science and Technology.

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Toxicity Analysis of Kava Extracts

Johnston, G. A. R., et al. (2019). Journal of Ethnopharmacology.

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Kava and Liver Safety

Teschke, R., & Lebot, V. (2011). Journal of Gastroenterology and Hepatology.

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Psychoactive and Toxic Properties

Araújo, C., et al. (2022). Molecules.

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Kava Quality Standardization

Teschke, R., & Lebot, V. (2011). Food and Chemical Toxicology.

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Kavalactone Validation Method

Geier, F. P., et al. (2018). Journal of AOAC International.

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🟠 Blue Turmeric: Bioactive Compounds & Safety

Key Takeaways

  • High Curcumin Content: Hawaiian blue turmeric varieties offer elevated curcuminoids (up to 60%), supporting antioxidant activity.
  • Proven Safety: Classified as GRAS by FDA; well-tolerated in studies with minimal side effects.
  • Anti-Inflammatory Support: Inhibits pathways like mTOR/PI3K, promoting balanced responses.
  • Quality Assurance: Water-dispersible extracts enhance bioavailability without harsh solvents.

Supporting Studies

Efficacy and Safety of Curcumin and Curcuma longa

Daily, M. K., et al. (2022). Nutrients.

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Role of Turmeric and Curcumin in Prevention

Pang, X., et al. (2023). Nutrients.

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Curcuma Longa: Traditional to Modern Applications

Kunnumakkara, A. B., et al. (2025). Chinese Medicine.

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Efficacy and Safety of Low-Dose Turmeric Extract

Gupta, S. C., et al. (2025). Journal of Pain Research.

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Turmeric and Curcumin Health Properties

Kowalik, K., et al. (2023). International Journal of Molecular Sciences.

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Therapeutic Potential of Curcuma longa

Kunnumakkara, A. B., et al. (2022). Frontiers in Pharmacology.

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🍃 Native Mamaki: Nutrients & Bioactivity

Key Takeaways

  • Nutrient-Rich Profile: High in potassium, calcium, magnesium, and antioxidants like polyphenols.
  • Antioxidant Activity: Supports cellular protection and anti-inflammatory responses.
  • Traditional Bioactivity: Potential anti-infectious and chemopreventive properties from Hawaiian studies.
  • Quality Assurance: Endemic varieties verified for mineral content and safety in infusions.

Supporting Studies

Comprehensive Insight into Māmaki

Gonçalves, S., et al. (2023). Plants.

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Hawaiian Plants: Effects on Sleep, Anxiety, Mood

Kostecka, M., et al. (2023). Plants.

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Antioxidant, Anticancer Properties of Mamaki Tea

Gonçalves, S., et al. (2022). Antioxidants.

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Phytochemistry of Endemic Hawaiian Plants

Gonçalves, S., et al. (2023). International Journal of Molecular Sciences.

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Nutrient Composition of Mamaki Leaves

Hosoya, T., et al. (2009). Journal of Food Composition and Analysis.

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Nutrients and Polyphenols in Mamaki

Chun, O. K., et al. (2006). Journal of Food Composition and Analysis.

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